Breaking the cycle. A GSK744 injection can cause infection for months by inhibiting the integration of HIV.
G.Grullón / Science
Antiretroviral drugs can protect people against infection with HIV. But so-called pre-exposure prophylaxis, or PrEP, only works if people take pills daily, which studies show they have trouble doing. Now the monkey experiments with an integrase inhibitor that is injected show how one shot protects against the AIDS virus for 11 weeks on average. The drug lasts even longer in humans, which may provide a promising new approach for PrEP.
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