Scientists grow tiny human stomachs in lab dishes

19:50
Scientists grow tiny human stomachs in lab dishes -

The colorful snakelike image above is actually fluorescently labeled tissues from a section of a stomach that is smaller a pea. But he stomach of an extraordinary little animal; it's a mini-cultured human stomach in a dish by scientists who hope to use it to study the gastrointestinal diseases. Because the digestive systems of mice, flies and other model organisms different from those of humans, researchers have struggled to find a way to study the development of human intestinal diseases such as peptic disease duodenal. Thus, several groups have turned to the derived pluripotent stem cells-cells of human embryos or reprogrammed adult cells that can develop into any type of cell in the body to try to develop the digestive organs in the laboratory. Last week, a group of researchers announced the creation of a small intestine grown in the lab from stem cells. Today, one of the various reports of the online team in Nature they have perfected the recipe of molecules needed to coax the two types of stem cells to grow into small spheres which, despite their size, have all a stomach functional properties. When the researchers exposed the ministomachs to the bacteria Helicobacter pylori , infections that are blamed for many stomach ulcers and cancers, they saw the same molecular and cellular changes already known to occur in the scale of stomachs.

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