Today
is Sir James Black's birthday, a British pharmacologist who revolutionized the treatment of heart disease and ulcers of his discovery of two important drugs.
In an attempt to find a drug that would relieve the pain of angina, discovered black propranolol, which target beta receptors in the heart, preventing hormones like adrenaline to stimulate and increase the heart rate and oxygen demand. Others followed the discovery of a multitude of new beta-blockers for the treatment of heart attacks, hypertension and migraine. Black also discovered cimetidine b, a compound that calms stomach ulcers by blocking the receptors that stimulate gastric acid secretion.
Black was knighted in 1981 and received a share of the Nobel Prize in Physiology or Medicine in 1988 for its drug discovery.
[Source: Britannica Online ]
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