SAN FRANCISCO - As light a miniature oven in the body, scientists have created a compound that stimulates some of the fat cells to burn calories without forcing them to bear jogging, swimming or cycling. Chemical, described here today at the annual meeting of the American Chemical Society, took up the metabolic rate of rats by 30% - equivalent to a weight loss of nearly 3 kilograms per month among people. But it may take several years before the potential drug comes on the market, and even when it does, the researchers caution that this is not a "magic pill" for slenderness.
The compound mimics adrenaline, the hormone messenger of the "fight or flight" response to danger. A type of adrenaline receptor starts the heart beat faster, and a second dilates blood vessels and lowers blood pressure. In 1989, a third receiver - the so-called 
A team led by Robert Dow Pfizer in Groton, Connecticut, studied
obesity experts are encouraged that so powerfully composed stokes the furnaces of brown fat cells. "This is a big step forward," said Xavier PiSunyer Columbia University Medical School. However, he noted, many obstacles remain, including the fact that human adipose tissue a few brown fat cells. To work in people, normal fat cells will respond to the drug, too.
If the drug was to be conducted in clinical trials, it would probably be prescribed as part of a plan, including regime change food and exercise, said Dow, who stressed that the drug is unlikely to be a magic bullet. "the idea of a pill to cure obesity is probably not going to come to be," he said .
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