Fatal contraction

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Fatal contraction - excitation-contraction coupling in the heart, then and now. (A) Classic, common-pool theory of EC coupling. (B) current, local mechanism EC coupling control. (C) Defects in the EC coupling during cardiac dysfunction. The researchers found...

Tumor-wading Gene Nabbed at Last

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Tumor-wading Gene Nabbed at Last - Researchers have finally been able to make charges stick against a tumor suppressor gene long suspected. The gene, called NF1 , was identified in 190 as the culprit in neurofibromatosis (NF), a disfiguring and potentially fatal disease that affects one in 3500....

Clinical Research Trials and Tribulations

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Clinical Research Trials and Tribulations - W ASHINGTON , DC - New therapies and treatments for diseases are compromised by a decline money, time, and training for clinical research, scientists said today at a joint meeting convened by the Institute of Medicine (IOM). Gaps in Clinical Research...

Doctors Call for Live-test HIV vaccine

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Doctors Call for Live-test HIV vaccine - A vaccine that AIDS has had more success in monkey experiments that any other approach has never been tested in humans. The reason: Many researchers believe the vaccine based on weakened - or attenuated - live virus, would be too risky. The International...

Turning Tumors in therapy

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Turning Tumors in therapy - A team of researchers immunized mice with proteins derived from their own cancer cells. The treatment, reported in tomorrow Science *, significantly slowed the spread of many types of cancer. A group of researchers from the University of Connecticut School of Medicine...

NIH Panel Commends Acupuncture

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NIH Panel Commends Acupuncture - W ASHINGTON DC - After decades of largely be repelled by the American medical establishment, acupuncture appears to be gaining some respectability. Last year, the Food and Drug Administration took the label off of acupuncture needles "experimental" as medical...

Cancer cells without future

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Cancer cells without future - W ASHINGTON , DC - Scientists have discovered a gene that some cancer cells destined to a period of limited life. Experts hope that the finding, reported this week at the American Society for the Annual Meeting of Cell Biology, could eventually lead to a new type...

Personalized Molecule radiotherapy improves

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Personalized Molecule radiotherapy improves - P HILADELPHIA - A molecule known for its Texas circumference now appears to be a promising new weapon against cancer . A pilot test of the new metal compound carrying heavy, described here Saturday at the annual meeting of the American Association...

Starting a Rout

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Starting a Rout - In one of the greatest moments in modern medical science, American microbiologist Jonas Salk, April 12, 1955 delivered safely its vaccine against polio newly invented and effective in almost 0% of cases. Salk discovered that injecting a small amount of killed virus induces the body...

mammary tumors Antibody Shrinks

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mammary tumors Antibody Shrinks - artificial antibodies can shrink tumors in women with advanced breast cancer, researchers announced yesterday at the American Society of Clinical Oncology meeting (ASCO) in Los Angeles. Experts said it is not yet known if treatment can extend patients' lives, but...

Elusive HIV Powers Growing

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Elusive HIV Powers Growing - The cracks are widening in the first line of defense against the virus that causes AIDS - drugs that inhibit the essential viral enzymes called proteases and reverse transcriptase. At the World Conference against AIDS 12 in Geneva, Switzerland, separate teams of US and...

An early marker for ovarian cancer?

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An early marker for ovarian cancer? - Scientists have identified a chemical in the blood that can indicate ovarian cancer at an early stage. If confirmed by larger studies, the finding may provide a way to detect ovarian cancer when the disease is most treatable. Because ovarian cancer usually...

NO News Is Good News for Medical Nobelists

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NO News Is Good News for Medical Nobelists - Three US researchers learned yesterday that they will share the Nobel Prize in Physiology or Medicine for his discovery that nitric oxide gas ( NO) acts as a messenger molecule in the body. The discovery led to the development of the drug to the popular...

AIDS Drug Policy of South Africa attracts criticism

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AIDS Drug Policy of South Africa attracts criticism - P ARIS - The controversy erupted on the southern government decision -africain retain the antiviral drug AZT to pregnant women infected with HIV - despite the compound to demonstrate efficacy in preventing HIV transmission to offspring AIDS...

Double Edge of Transplant Drugs

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Double Edge of Transplant Drugs - Malignant tumors in transplant patients are generally attributed to a weakened immune system by medication. But a study in tomorrow's issue of Nature shows that drugs can play a more direct role: A common immunosuppressive can stimulate tumor cells to divide and...

Herpes infection Soothing

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Herpes infection Soothing - The virus that causes herpes could one day provide relief, rather than misery. In today Proceedings of the National Academy of Sciences , biologists show that the herpes virus can shuttle human genes in nerve cells in mouse pain, increasing their tolerance to pain. If...

Dangers of a diet Roach

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Dangers of a diet Roach - Johannes Fibiger, a Danish pathologist and bacteriologist who improved public health and research on cancer revitalized, was born that day in 1867. early in his career, Fibiger discovered that there are two distinct forms of diphtheria, a disease that caused frequent...

Prevented Kidney Rejection in Monkeys

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Prevented Kidney Rejection in Monkeys - A new drug taken for a few months prevented monkeys rejecting transplanted kidneys. The drug described in the June Nature Medicine also lack the side effects of immunosuppressive drugs, such as increased susceptibility to infection. Human trials are just...

She started a baby boom

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She started a baby boom - Science now wants a happy 21st birthday of the first test tube baby, Louise Joy Brown, born in England 25 July 1978. Brown debuted through in vitro fertilization technique developed by the gynecologist Patrick Steptoe and physiologist Robert G. Edwards. The success has...

Evaluation Plan Peer AIDS breath NIH researchers

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Evaluation Plan Peer AIDS breath NIH researchers - W ASHINGTON, DC - A review by recasting program peers national Institutes of health (NIH) takes the intense fire of the AIDS community. Complaints activists patients and scientists have been accumulating for 2 weeks in the scientific review for...

Defend the mortal researchers Trial Gene

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Defend the mortal researchers Trial Gene - B ETHESDA , M ARYLAND - Doctors and scientists from University of Pennsylvania defended their clinical judgment today in the case of Jesse Gelsinger, 18, who died September 17 while receiving experimental gene therapy. At a meeting here, the National...

HIV Bodyguard Discovered

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HIV Bodyguard Discovered - HIV may well be the most studied virus of all time, but the steps between its introduction into the body through sexual intercourse and an established infection remains mysterious . Now, researchers reported intriguing evidence that a poorly understood protein may allow...

Matchmaking Drug Discovery

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Matchmaking Drug Discovery - T UCSON , A RIZONA - If the pharmaceutical companies are good at thing, there are tons of new molecules. In recent years they have embraced a technical producer of high-speed drugs known as combinatorial chemistry to multiply the new compounds by the millions. The...

Radical Steps Urged for Vaccine Development

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Radical Steps Urged for Vaccine Development - B ETHESDA , M ARYLAND - It is time for bold action to stimulate the development of vaccines for major killers in the world - AIDS, malaria and tuberculosis - according to a panel of experts convened here May 22 to 23 Technically, these vaccines are...

Mbeki Speech Angers AIDS researchers

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Mbeki Speech Angers AIDS researchers - D URBAN , S OUTH A AFRICA - When the south African president Thabo Mbeki has risen to meet the opening ceremony of the international AIDS Conference XIII yesterday, thousands of researchers in packed Kingsmead Stadium hoped he was going to say three simple...

Take xenografts Glancing Blow

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Take xenografts Glancing Blow - pig cells released an ancient virus when transplanted into mice lacking an immune system, according to results published in the August 17 issue of Nature . This transmission is a potential concern for xenotransplantation research, but there is still no evidence that...

Vaccine against AIDS protects monkeys

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Vaccine against AIDS protects monkeys - The enemy. a new vaccine counteracts HIV virus as in monkeys. a study in this week's issue of science showed that a new AIDS vaccine can protect monkeys from getting sick, providing new avenues for AIDS vaccine human....

Mutated Vaccine linked to a polio outbreak

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Mutated Vaccine linked to a polio outbreak - Good vaccine wrong. A recent polio outbreak was linked to a vaccine of virus that became contagious. a vaccine to protect children against polio have instigated a recent outbreak of the disease in the Dominican Republic...

Hopkins paris on

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Hopkins paris on - stem cells Johns Hopkins University in Baltimore is placing a big bet that the hot field of cell therapies will pay off. The university announced Tuesday it would use a $ 58.5 million gift from an anonymous donor to launch an ambitious cell Engineering Institute. Its researchers...