Winner. Arnold Levine takes home the first prize Albany.
When the Albany Medical Center in New York announced last November that it would assign a new annual award in biomedical research, something made the price stand out: a cool half million dollars. Now the center has given its top prize on Arnold Levine, president of Rockefeller University in New York and co-discoverer of a protein that goes wrong in cancer.
The award was established with a gift of $ 50 million to the Albany Medical Center in Morris Silverman, a businessman from New York who was educated near Albany. The award recognizes researchers who have made important contributions to medicine and biomedical research. It is the largest annual award in science or medicine in the US, according to a spokesman Albany door probably only a second award for the Nobel Prize, which last year was worth $ 915,000.
Levine won the award, announced on March 14, for his contribution to cancer biology. In 1979, p53, a protein that is defective in more than 50% of co-discovered human cancers. The protein normally cleans up after the cells with damaged DNA by clamping down on cell division or inducing cell suicide; otherwise, cancer cells proliferate. Levine has not only helped to recognize the role of p53 in cancer, he also played a leading role in the cloning of the first DNA p53 and identification of a key protein that binds p53 and modulate its function. It is now testing compounds that could kick a defective p53 protein back in action or crank up the amount of p53 available to limit the damage.
"Arnie has made a fundamental contribution to each step in the development of the p53 field," said Frank McCormick, director of the University of California, San Francisco Comprehensive Cancer Research Center and author of several reviews p53. He praises Levine for an open and collaborative style of research that has influenced many p53 researchers. "In such a competitive field this is a major achievement in itself," said McCormick.
Related Sites
The Albany Price Medical Center
Rockefeller University
More on p53
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