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Summary
Nearly 20 years ago, researchers have made of nucleic acids in the third dimension. Normally, DNA extracts and RNA resemble small chains. But the researchers found that when they have linked dozens of identical nucleic acid strands to a tiny metal nanoparticle, they formed nucleic acid particles that resembled tiny Koosh balls, with a solid core and flexible strands who exit. The particles with complementary nucleic acids bonded together, forming 3D materials. But what was more surprising was that the cells took the particles easily. Once inside the cells, spherical nucleic acids (SNA) can bind to RNA and DNA within cells, disabling the production of specific proteins. It has since been used to treat everything from cancer to psoriasis. Now a center at Northwestern University in Evanston, Illinois, received $ 11.7 million to continue SNA therapies, and human clinical trials with the particles should begin this fall.
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