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Summary
the blood-brain barrier, a busy layer of cells lining the blood vessels of the brain, protects against infections, toxins and other threats, but makes the frustrating organ difficult to treat. A strategy that combines ultrasound with microscopic blood bubbles may briefly open the gate, in theory give medication or access of the immune system in the brain. This month, neurosurgeons hope to use ultrasound to deliver a dose of chemotherapy for a malignant brain tumor in one of the first clinical trials of the technique. And some elements of the most dramatic evidence of the potential of the technique, a research team reports this week Science Translational Medicine they used to rid mice of abnormal clumps in the brain similar to those of Alzheimer's disease, restoring lost memory and cognitive function.
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