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Summary
in the 1950s, researchers found that when the flow of a young mouse is connected to an old mouse, the older pet seems to be rejuvenated. Since 05, a handful of laboratories have been strongly pursue the molecules responsible, hoping to use them to slow or reverse aging in people. One in particular stood out: a protein found in the blood known as young GDF11. In several high-level documents, two of them published last year in Science , a Harvard University team said the GDF11 levels decline in older animals, and replacing rebuilds muscles, brain and heart. But the work described this week Cell Metabolism by Novartis team contests GDF11 rejuvenation powers. Their paper casts doubt on the tests used in previous research and suggests that GDF11 actually inhibits muscle regeneration.
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