The curing or prevention of complex diseases is one of the most ambitious health goals Here. Since the late 190s, researchers tried-and mostly failed to accomplish this in type 1 diabetes, an immune disease that destroys the pancreas cells that make insulin, which mainly affects children. This summer, a large number of new studies reported the results of efforts to change the balance of immune system cells in hopes of keeping the disease at bay. The results show how difficult it is to intervene successfully. Why is it so difficult to get from a scientific discovery to a new drug? Is the prevention of diseases difficult or easier than treating patients who have already? What does the road look like?
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Jay S. Skyler
Jeff Bluestone
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