Ronald DePinho
the University of Texas MD Anderson Cancer Center
the controversy over grant $ 20 million incubator made in March by the Institute of $ 3 billion cancer prevention and research of Texas (CPRIT) at two universities of Texas continues to be felt. This week, the President of the University of Texas MD Anderson Cancer Center has publicly responded to the rumor, and the press has raised new questions about how the grant was presented and discussed.
As we reported last week, up $ 18 million of the grant goes to a discovery center co-directed drugs by Lynda Chin, wife of MD Anderson President Ron DePinho. The rest will fund a marketing center at Rice University. On May 8, the scientific director of CPRIT, Nobel Alfred Gilman prices, announced he resigned in part because other CPRIT leaders decided that the party MD Anderson (proposal and notes) did not include research and does not need to go through a scientific review. scientific examination of members of CPRIT board wrote CPRIT the board say they shared the concerns of Gilman.
New this week:
- The Houston Chronicle reported that two members of the review of the marketing board CPRIT had links with Rice. One is listed on the Rice proposal as a "leading member" and another is on its "strategic investment committee." CPRIT responded to the suggestion of conflict of interest in a letter to investigators, saying neither members participated in the examination of the proposal.
- the Houston Chronicle published responses DePinho and executive CPRIT DirectorWillam Gimson an editorial he wrote raising questions about the price. in the letter DePinho, he repeats the argument that the decision on how to revise the subsidy came down to a difference of opinion on the objectives of the Institute of applied science Cancer (IACS .) in his letter:
IACS is a game changer - not a traditional search business - which provides a robust drug development pipeline successfully ...
.MD Anderson and Rice have applied for the grant on the basis of a request for proposals issued by CPRIT. Our final proposal presented a solid business strategy for improving drug development and new business creation. The proposal received four notices pending competent people outside of Texas. Because it is not a research project, not deep science was included. ...
[The] IACS is a new hybrid model that combines the best features of academia and industry in a coherent organization. With its professional staff of seasoned industry numbering 56, IACS leads activities resulted stringent steps oriented goals with sufficient resources are allocated to programs with the highest level of long-term success in the clinic.
Some "research." May choose to call our proposal we call business, and we are confident Texans will be the beneficiaries.
- The Letter cancer , a newsletter based in Washington DC, announced today that the grant application does not pass by the office of MD Anderson provost Raymond DuBois before it was submitted to CPRIT (subscription only, but excerpts here). The newsletter suggests that it is "unusual" because the plans of IACS include animal studies and clinical trials at early stage, and because Chin DePinho works for the written report:
Bypass examination by a provost of the institution that employs the researcher seeking funds is very unusual and problematic, especially when medical research is involved, and more in situations where there is a risk of conflicts arising from nepotism, ethics experts and review of subsidies say.
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