An inherited form of ovarian cancer may be less lethal than other versions of the disease, according to a study published in the today the New England Journal of Medicine . A group of 53 women who have inherited mutations in the BRCA1 gene, which causes only a small fraction of ovarian cancer had a median survival - the point where half the group died - 77 months after diagnosis compared to 29 months for women of the same age and type of tumor that had no family history of cancer and no signs of mutation.
scientists do not fully understand how BRCA1 gene works, and authors of the study, 12 researchers from five medical institutions, do not speculate on the mechanisms behind the best rate survival. But the discovery may lead to new research leading to better treatments for women with cancers induced mutation says co-author Henry Lynch, a medical oncologist at the University of Medicine School Creighton in Omaha, Nebraska.
Lynch calls the `` results striking, but not surprising. '' He said he and other researchers have found high rates of survival similar to hereditary breast cancer and colon cancer. Joseph Marcus, a pathologist at St. Luke's Hospital in St. Louis, also said the study is in line with previous research. Ironically, he and his colleagues found that breast cancer cells with BRCA1 mutation divide faster than other tumor cells are normally a sign of a deadly cancer.
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